Resource Summary

Clinical Question:
Can cell free DNA (CF-DNA) be recommended to women to screen for trisomies?

Bottom Line:
Best evidence suggests that CF-DNA testing at 10-14 weeks is more sensitive (100 percent) and specific (99.9 percent) than current screening for Trisomy 21 and approaches accuracy of amniocentesis. Implementation of CF-DNA may be limited by cost and provincial coverage.


*** Original Documents can be found and downloaded using the link provided below ***

https://www.acfp.ca/tools-for-practice/

Publication Date: 2016-7-4
Last Updated on PCR: 2017-03-31 16:20:11