Are benzodiazepines effective in generalized anxiety disorder (GAD)?
In GAD^ benzodiazepines are more effective than placebo and similar to antidepressants. They cause more withdrawals for adverse effects than placebo but less than antidepressants. They are recommended second-line generally due to concerns of dependence. The evidence quality is generally poor^ trials are short-term^ and none used benzodiazepines as adjunctive therapy.
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Publication Date: 2015-4-27
Last Updated on PCR: 2017-03-31 14:39:19