Resource Summary

Clinical Question:
Is buprenorphine (with or without naloxone) effective as maintenance therapy in pharmaceutical opioid use disorder?
Bottom Line:
Retention in treatment at 15 weeks was seen in 75% taking buprenorphine compared to 26% in detoxification and/or counselling^ with 37% reporting ongoing substance use compared to 60% in control. Outcomes between buprenorphine and methadone in this population are similar. The evidence is at moderate to high risk of bias.

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Publication Date: 2018-11-5
Last Updated on PCR: 2018-11-06 14:14:24