Resource Summary

Clinical Question:
Does the trivalent influenza vaccine (flu shot) prevent influenza or its complications in healthy working age adults?

For healthy adults^ the flu shot reduces influenza when vaccine is well matched to circulating influenza strains (Numbers Needed to Treat (NNT)=12-37). When vaccine is poorly matched^ effectiveness diminishes and may be similar to placebo. The flu shot has not been shown to affect hospitalizations and observational evidence that influenza vaccine decreases mortality is likely biased.

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Publication Date: 2013-11-12
Last Updated on PCR: 2017-03-31 15:39:48