How effective is the pneumococcal vaccine in preventing pneumonia or other clinically important outcomes in adults?
At best^ pneumococcal vaccines may prevent pneumonia for an additional 1 in 55 adults and 1 in 20 COPD patients^ and COPD exacerbations for 1 in 8^ over ~3 years. Pneumococcal 23 polysaccharide vaccine (PPV23) prevents pneumonia for 1 in 13 long- term care residents. Pneumococcal 13 conjugate vaccine (PCV13) does not decrease pneumonia. No systematic review of randomized controlled trials (RCTs) or high-quality RCTs found a reduction in mortality.
Publication Date: 2018-7-30
Last Updated on PCR: 2018-08-18 10:21:11