Resource Summary

Clinical Question:
Is pregabalin effective for generalized anxiety disorder (GAD)?
Bottom Line:
Evidence for pregabalin in GAD is inconsistent and at high-risk of bias (industry-written^ short-term^ poorly described methods^ high drop-outs^ and run-in periods that overinflate benefit). If real^ an additional one in 6-8 people may respond to pregabalin compared to placebo at 4-8 weeks. However^ the change in anxiety scales was not clinically meaningfully different than placebo for the average patient.

Publication Date: 2018-7-16
Last Updated on PCR: 2018-07-24 15:47:58