Resource Summary

Clinical Question:
Are leukotriene receptor antagonists (LTRAs) effective in pediatric asthma?

Bottom-line:
Using leukotriene receptor antagonists instead of inhaled corticosteroids as monotherapy will lead to one more exacerbation in every 21 patients. As add-on to inhaled corticosteroids^ leukotriene receptor antagonists are inferior to long acting beta-agonists (LABAs)^ and show similar outcomes to increased doses of inhaled corticosteroids (ICS). Data is limited and not supportive of use in children ≤5 years.


*** Original Documents can be found and downloaded using the link provided below ***

https://www.acfp.ca/tools-for-practice/

Publication Date: 2016-1-18
Last Updated on PCR: 2017-04-01 11:53:19