Resource Summary

Clinical Question:
Are leukotriene receptor antagonists (LTRAs) effective in pediatric asthma?

Using leukotriene receptor antagonists instead of inhaled corticosteroids as monotherapy will lead to one more exacerbation in every 21 patients. As add-on to inhaled corticosteroids^ leukotriene receptor antagonists are inferior to long acting beta-agonists (LABAs)^ and show similar outcomes to increased doses of inhaled corticosteroids (ICS). Data is limited and not supportive of use in children ≤5 years.

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Publication Date: 2016-1-18
Last Updated on PCR: 2017-04-01 11:53:19