Resource Summary

Clinical Question:
Are daily prophylactic antibiotics a reasonable option in preventing acute exacerbation of COPD (and if so^ which patients)?

In selective patients with severe COPD and recurrent exacerbations^ prophylactic antibiotics may reduce exacerbations for about 1 in 10. Balanced against possible increased resistance and adverse events^ present use should be very limited. The long term benefits and impacts on antimicrobial resistance remain to be seen.

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Publication Date: 2012-2-21
Last Updated on PCR: 2017-03-31 15:26:04