Resource Summary

Clinical question:
Is metformin a reasonable alternative to insulin in gestational diabetes mellitus (GDM)?

Bottom Line:
Compared to insulin^ metformin results in 1kg less maternal weight gain and less severe neonatal hypoglycaemia for one in 22 babies^ but results in earlier delivery by about one day. Other clinical outcomes are unchanged and long-term safety of metformin in GDM appears reassuring. Metformin is a reasonable option in GDM requiring treatment.

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Publication Date: 2015-10-13
Last Updated on PCR: 2017-03-31 14:17:04