Resource Summary

Clinical Question:
Do different non-steroidal anti- inflammatory drugs (NSAIDs) have different cardiovascular risks?

Bottom-line:
COX-2 inhibitors and traditional NSAIDs^ except naproxen^ increase the risk of major vascular events and death. When prescribing NSAIDs^ patients’ gastrointestinal (GI) and cardiovascular (CV) risk should be assessed^ with naproxen or low-dose ibuprofen preferentially chosen for patients at risk of CV disease.


*** Original Documents can be found and downloaded using the link provided below ***

https://www.acfp.ca/tools-for-practice/

Publication Date: 2013-11-18
Last Updated on PCR: 2017-03-31 16:21:56