Resource Summary

Clinical Question:
Which commonly used topical therapies (cryotherapy^ 5-Fluorouracil^ imiquimod^ or ingenol) are preferred for actinic keratosis?
Bottom Line:
Topical treatments have similar efficacy to each other and will result in complete clearance of lesions beyond placebo for every 3-4 patients treated. Clearance rates may reach ~90% depending on strength of cream (5% 5-fluorouracil [5FU] greater than 0.5%)^ longer duration of therapy^ and complexity of lesion. The effects on cancer incidence have not been studied.

Publication Date: 2018-1-29
Last Updated on PCR: 2018-02-02 07:17:04