Resource Summary

Clinical Question:
Do non-steroidal anti-inflammatory drugs (NSAIDs) increase the risk of fracture non-union or impede healing?

Limited RCT data suggests that NSAIDs do not impair fracture healing. Cohort studies associating NSAID use with fracture non-union are likely demonstrating that patients with non-healing (and painful) fractures are just using more analgesics. As NSAIDs provide equivalent or superior acute pain relief to other common analgesics often with fewer adverse effects^ patients should not be denied their short-term use in fracture management.

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Publication Date: 2014-5-26
Last Updated on PCR: 2017-03-31 16:17:43