Resource Summary

Clinical Question:
Do tetrahydrocannabinol (THC)^ cannabidiol (CBD)^ or the THC/CBD combination yield differing benefits or harms?
Bottom Line:
From four randomized controlled trials (RCT)^ one found THC/CBD superior to THC but this was inconsistent within study and with other studies. Adverse events are prevalent in THC/CBD and individual components. While some early poor-quality research in healthy users suggest CBD may attenuate some psychiatric effects of THC^ better research in real patients is needed to verify any benefits of specific components.

Publication Date: 2018-4-23
Last Updated on PCR: 2018-04-25 16:20:08