Resource Summary

Clinical Question:
Does daily riboflavin (vitamin B2) prevent migraines?
Studies of riboflavin are inconsistent and often have high placebo response rates. Most randomized^ controlled trials (RCTs) found no reduction in migraine frequency. One study found for every three adults treated with riboflavin^ one patient would have a ≥ 50% reduction in migraine frequency compared to placebo. Adverse effects are poorly reported^ but include diarrhea and discoloured urine.

Publication Date: 2017-8-14
Last Updated on PCR: 2017-08-14 10:16:01