Resource Summary

Clinical Question:
What is the evidence to support gabapentin (or pregabalin) in chronic peripheral neuropathic pain?

The apparent benefit of gabapentin in chronic pain was exaggerated by publication and reporting biases. In carefully selected patients with peripheral neuropathic pain^ gabapentin may offer moderate or more pain relief for one in every 6–8 patients but causes adverse events in a similar number. There is no trial evidence pregabalin is superior to gabapentin.

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Publication Date: 2013-10-22
Last Updated on PCR: 2017-03-31 15:53:48