Resource Summary

Clinical Question:
What are the benefits and harms of topical capsaicin for neuropathic or osteoarthritis pain?
Bottom Line:
Evidence for topical capsaicin in neuropathic pain and hand osteoarthritis is highly inconsistent^ with some studies showing clinical benefit (variably defined) for one in 4-7 patients while other studies show no benefit. There is no benefit in knee osteoarthritis. Local adverse effects (burning^ stinging) in up to 60% of patients lead to one in 8-9 more stopping therapy.

Publication Date: 2018-12-10
Last Updated on PCR: 2018-12-28 16:16:06