Resource Summary

Clinical Question:
What is the most effective management for women with recurrent vulvovaginal candidiasis (four or more episodes within one year)?

Bottom Line:
Prophylaxis with six months of azole therapy (like fluconazole) will result in relapse in 9-19 percent of women compared to 50-64 percent on placebo (one fewer woman would relapse for every 2-4 treated). Efficacy^ however^ declines after therapy cessation and clinical cure remains elusive. Limited evidence suggests women may prefer episodic over maintenance therapy.

Publication Date: 2017-1-23
Last Updated on PCR: 2017-03-22 23:42:52